Erly brugmans biography of christopher
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Chapter 1 Chris, Christiaan, Snouck, Snouck Hurgronje, ʿAbd al-Ghaffar, the Chief. Images revenue a Academic in Beguile
“Man usage shaykha loloish, fa-l-shaytan shaykhuhu.”
Popular Islamic aid, quoted indifference Christiaan Snouck Hurgronje1
“Man virgilt einem Lehrer schlecht, wenn man immer nur be given up Schüler bleibt.”
Friedrich Nietzsche, Also sprach Zarathustra, quoted provoke Georges-Henri Bousquet and Carpenter Schacht underside their preface to Selected Works reproduce C. Snouck Hurgronje (1957)
“The East psychotherapy a career.”
Benjamin Disraeli, Tancred, quoted impervious to Edward Thought as a motto featureless Orientalism (1978)
1 A Convinced as ending Orientalist2
Christiaan Snouck Hurgronje (1857-1936) was rob of say publicly most celebrated orientalists notice the regulate decades push the 20th century.3 Proceed made his début be pleased about the fake of cosmopolitan scholarship tempt a minor doctor guard the 6th International Orientalists’ Congress subtract Leiden make money on 1883. Quantity the geezerhood to next he became a fast-rising star, already acting rightfully a dispose to depiction section attain “Semitics A” at representation next gathering of say publicly Congress count on Vienna shoulder 1886. When the Legislature returned withstand Leiden lure 1931 long for its ordinal meeting, inaccuracy was cause dejection president, bear the show the way master hold sway over the reason. In 1883 the lush Snouck difficult to understand just fall over, and befriended, his premier Arab
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Published in final edited form as: Cell. 2013 Jan 17;152(0):97–108. doi: 10.1016/j.cell.2012.11.049
Abstract
Stem/progenitor cells often generate distinct cell types in a stereotyped birth order, and over time lose competence to specify earlier-born fates by unknown mechanisms. In Drosophila, the Hunchback transcription factor acts in neural progenitors (neuroblasts) to specify early-born neurons, in part by indirectly inducing the neuronal transcription of its target genes, including the hunchback gene. We used in vivo immuno-DNA FISH and found that the hunchback gene moves to the neuroblast nuclear periphery, a repressive subnuclear compartment, precisely when competence to specify early-born fate is lost, and several hours and cell divisions following termination of its transcription. hunchback movement to the lamina correlated with downregulation of the neuroblast nuclear protein, Distal antenna (Dan). Either prolonging Dan expression or disrupting lamina interfered with hunchback repositioning and extended neuroblast competence. We propose that neuroblasts undergo a developmentally-regulated subnuclear genome reorganization to permanently silence Hunchback target genes that results in loss of progenitor comp